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Sarah J. Wherry, Cheryl Der Ananian and Pamela D. Swan

fall-related fractures in older people: a meta-analysis of randomized controlled trials . Int J Epidemiol . 2017 ; 46 ( 1 ): 149 – 161 . PubMed ID: 27477031 27477031 17. Pettee Gabriel K , McClain JJ , Lee CD , et al . Evaluation of physical activity measures used in middle-aged women

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Carolee Winstein

randomized controlled trials (RCTs) of complex interventions for recovery should be an imperative ( Campbell et al., 2000 ). We return to the issue raised earlier, “social and personal factors can have a high impact on stroke recovery in humans….and are not well modelled in preclinical research”. One noted

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Tyler L. Malone, Adam Kern, Emily Klueh and Daniel Eisenberg

relative to articles for both coping strategies. To test both hypotheses, we used a randomized controlled trial to compare video- and text-based interventions designed to deliver coping skills information to college student-athletes. Method Participants We recruited study participants via e-mail from all

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Andy J. King, Joshua T. Rowe and Louise M. Burke

hydrogel treatment. Despite marketing claims and lay media discussion about MD + F products in hydrogel format, currently available studies fail to show benefits in terms of muscle oxidation of exogenous CHO, GI comfort, or performance. The current literature, comprised of robust randomized controlled

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Brad Donohue, Yulia Gavrilova, Marina Galante, Elena Gavrilova, Travis Loughran, Jesse Scott, Graig Chow, Christopher P. Plant and Daniel N. Allen

health help-seeking in elite athletes: An exploratory randomized controlled trial . Journal of Medical Internet Research, 14 ( 3 ), 69 . doi:10.2196/jmir.1864 10.2196/jmir.1864 Gulliver , A. , Griffiths , K.M. , Mackinnon , A. , Batterham , P.J. , & Stanimirovic , R. ( 2015 ). The mental

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Bradley M. Wipfli, Chad D. Rethorst and Daniel M. Landers

A meta-analysis was conducted to examine the effects of exercise on anxiety. Because previous meta-analyses in the area included studies of varying quality, only randomized, controlled trials were included in the present analysis. Results from 49 studies show an overall effect size of -0.48, indicating larger reductions in anxiety among exercise groups than no-treatment control groups. Exercise groups also showed greater reductions in anxiety compared with groups that received other forms of anxiety-reducing treatment (effect size = -0.19). Because only randomized, controlled trials were examined, these results provide Level 1, Grade A evidence for using exercise in the treatment of anxiety. In addition, exercise dose data were calculated to examine the relationship between dose of exercise and the corresponding magnitude of effect size.

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George A. Kelley and Kristi S. Kelley

The purpose of this study was to use the meta-analytic approach to examine the effects of exercise on resting systolic and diastolic blood pressure in children and adolescents. Twenty-five studies that included 84 groups (45 exercise, 39 control) and 3,189 subjects (1,885 exercise, 1,304 control) met the criteria for inclusion. Using a random effects model, non-significant decreases of approximately 2% were found for resting systolic (mean – SEM, –2 – 1 mmHg, 95% CI, –4 to 1 mmHg) and diastolic (mean – SEM, –1 – 1 mmHg, 95% CI, –3 to 1 mmHg) blood pressure. Greater decreases in resting systolic blood pressure were found for nonrandomized versus randomized controlled trials (p = 0.001). There was also a statistically significant association between changes in resting systolic blood pressure and initial blood pressure (r = 0.73, p < 0.001) and body weight (r = 0.64, p < 0.001). However, when limited to randomized trials, these results were no longer statistically significant. The results of this study suggest that exercise does not reduce resting systolic and diastolic blood pressure in children and adolescents. However, a need exists for additional randomized controlled trials, especially among hypertensive children and adolescents.

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Gina Bravo, Pierre Gauthier, Pierre-Michel Roy, Hélène Payette, Marie-France Dubois, Monique Harvey and Philippe Gaulin

A recently completed randomized controlled trial documented the effects of a 1-year group-based exercise program in osteopenic women. The present study concerns the comparison of these effects to those produced by a home-based exercise program tested on the same population. All 63 women who had been randomly assigned to the control group in the previous study were invited to enroll in the home program. Comparison of pre- and posttest scores of home exercisers revealed improvements in agility and well-being. In comparison, women who had participated 1 year earlier in the group-based exercise program had improved on four of the five fitness tests, well-being, and pain intensity. More women in the group-based exercise program showed improvement in self-rated health in comparison to those enrolled in the home program. Results suggest that for osteopenic women, a group-based exercise program is much more effective than a home-based exercise program.

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Carolyn Rabin, Bernardine M. Pinto and Georita M. Frierson

Physical activity (PA) interventions diminish some of the physical and psychosocial sequelae of breast cancer diagnosis and treatment. To increase intervention efficacy and portability, it is necessary to determine the factors mediating intervention effects on physical and psychosocial outcomes. This study presents mediator analyses from a randomized controlled trial of a home-based PA intervention (focused primarily on brisk walking) for breast cancer survivors. Eighty-six survivors were randomized to PA or contact control groups (mean age = 53.42 years, SD = 9.08 and 52.86 years, SD = 10.38 respectively; mean time since diagnosis < 2 years). The PA intervention was based on the transtheoretical model (TTM). Kraemerʼs approach was used to test hypothesized mediators. TTM variables did not mediate intervention effects on PA. Data indicate that increases in moderate-intensity PA and improved fitness may mediate intervention effects on vigor (β = .21; p = .01) and fatigue (β = .24; p = .05) and suggest the value of future research on these potential mediators.

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Erwin C.P.M. Tak, Jannique G.Z. van Uffelen, Mai J.M. Chin A Paw, Willem van Mechelen and Marijke Hopman-Rock

After a randomized controlled trial showing that improvement on some aspects of cognitive function was related to adherence to an exercise program, determinants of adherence and maintenance were further studied. Older adults with mild cognitive impairment were contacted 6 mo after the end of exercise programs for a telephone interview addressing patterns of adherence and determinants of maintenance. Mean adherence during the trial was 53%. About one third of participants had lapses during the trial but completed, one third had no lapses, and one third dropped out or never started. Practical barriers (time, location) were related to not starting and functional limitations to dropout. After the trial 25% of participants continued the programs, 14% reported intention to continue, and 61% quit. Maintenance was determined by fewer health complaints, higher satisfaction with the programs, and better adherence during the programs. Although maintenance was low, this study identified several reasons and barriers to adherence and maintenance that could be addressed.