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Claire E. Badenhorst, Katherine E. Black and Wendy J. O’Brien

increase in hepcidin levels occurring 5 hr after starvation commenced, and it was sustained for the duration of the starvation period (48 hr). This novel method of HAMP induction and subsequent burst at 5-hr poststarvation is largely the result of CREBH binding to the HAMP gene. The maintenance of

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Joel Garrett, Stuart R. Graham, Roger G. Eston, Darren J. Burgess, Lachlan J. Garrett, John Jakeman and Kevin Norton

sustainment of performance output, while also minimizing excessive muscle damage. Along with NMF having an effect on the ability to sprint, decreases were observed within the mediolateral vector (PL1D side ) and anteroposterior vector (PL1D fwd ). This may mean that either directly, or due to modifications in

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Tatiane Piucco, Fernando Diefenthaeler, Rogério Soares, Juan M. Murias and Guillaume Y. Millet

(Figures  4A and 4B ), indicating a close pattern of physiological demand. A relatively large plateau in V ˙ O 2 versus workload relationship was observed for most of the tests. Foster et al 22 pointed out to the remarkable ability of the skaters to rapidly attain and sustain maximal level of V ˙ O 2

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Scott Cocking, Mathew G. Wilson, David Nichols, N. Timothy Cable, Daniel J. Green, Dick H. J. Thijssen and Helen Jones

ischemic conditions, 2 it remains unknown whether previously observed local IPC-induced metabolic adaptations 9 , 30 may have contributed to these findings. Nevertheless, the current data are suggestive that traditional IPC, applied locally, enhances the ability to sustain the same workload for a

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Jose A. Rodríguez-Marroyo, José G. Villa, Raúl Pernía and Carl Foster

protocols. 2 Also, a large capacity to sustain high intensities during prolonged submaximal work has been reported. For example, the ventilatory (VT) and respiratory compensation (RCT) thresholds have been measured at ∼70% and ∼90% of VO 2 max, respectively, 1 – 3 and a gross efficiency of ∼24% has been

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Bianca Miarka, Fábio Dal Bello, Ciro J. Brito, Fabrício B. Del Vecchio, John Amtmann and Karim Chamari

, early detection, early treatment of health problems), and tertiary prevention (ie, reducing complications associated with already sustained health problems). 17 A translating research into injury prevention practice framework model is looking at primary prevention. 17 In some cases, injury has occurred because

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Thomas Reeve, Ralph Gordon, Paul B. Laursen, Jason K.W. Lee and Christopher J. Tyler

the present study was only 38.3°C (0.4°C). Other high-intensity STHA studies reported similar thermal impulses and also failed to achieve a sustained elevation in body core temperature ≥38.5°C resulting in minimal physiological adaptations. 9 – 11 In combination, these data suggest that short

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Alison Keogh, Barry Smyth, Brian Caulfield, Aonghus Lawlor, Jakim Berndsen and Cailbhe Doherty

cost of running 1 (2.8) 2 (1.8) Lactate concentration at turnpoint 1 (2.8) 2 (1.8) Maximal sustainable fraction of VO 2 max 1 (2.8) 2 (1.8) Velocity where lactate goes above baseline 1 (2.8) 2 (1.8) Ventilatory threshold 1 (2.8) 2 (1.8) VO 2 max at lactate threshold 1 (2.8) 2 (1.8) Annual training

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Matthew Ellis, Mark Noon, Tony Myers and Neil Clarke

action of adenosine, which increases cell activity. 5 Direct antagonism of adenosine receptors may improve aerobic performance through enhanced excitation–contraction coupling through increased release of Ca 2+ from the sarcoplasmic reticulum. 6 Similarly, it can reduce pain perception and sustain

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Daria Neyroud, Jimmy Samararatne, Bengt Kayser and Nicolas Place

, if during voluntary dynamic contractions some motoneurons might discharge at a very high rate during the first 2 to 3 pulses, 15 , 16 the firing frequency rapidly declines and the concomitant application of NMES might allow motoneurons to sustain higher discharge rates. 17 As such, the application