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André L. Estrela, Aline Zaparte, Jeferson D. da Silva, José Cláudio Moreira, James E. Turner and Moisés E. Bauer

. , Bertoni-Freddari , C. , Collins , A. , … Astley , S.B. ( 2002 ). Biomarkers . Molecular Aspects of Medicine, 23 ( 1–3 ), 101 – 208 . PubMed 10.1016/S0098-2997(02)00017-1 Gutteridge , J.M. , & Halliwell , B. ( 2000 ). Free radicals and antioxidants in the year 2000. A historical look to the

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Tom Clifford

, 1990 ). These findings provide support for the “free radical theory of aging,” which suggests that the age-related increased generation of RS progressively damages cellular structures and curtails the life span ( Cui et al., 2012 ). From a muscle damage context, it has been suggested that the cells

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Dariush Sheikholeslami-Vatani, Slahadin Ahmadi and Hassan Faraji

Aging is a physiological process that adversely affects most biological functions and results in reduced resistance to cellular stress. Furthermore, aging is characterized by an increased production of free radicals in several tissues, which might promote systemic cellular apoptosis followed by

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Thiago Correa Porto Gonçalves, Atila Alexandre Trapé, Jhennyfer Aline Lima Rodrigues, Simone Sakagute Tavares and Carlos Roberto Bueno Junior

: 10.1161/CIRCULATIONAHA.107.760405 Pinheiro , L.C. , Montenegro , M.F. , Amaral , J.H. , Ferreira , G.C. , Oliveira , A.M. , & Tanus-Santos , J.E. ( 2012 ). Increase in gastric pH reduces hypotensive effect of oral sodium nitrite in rats . Free Radical Biology and Medicine, 53 ( 4

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Melissa E. Hay and Denise M. Connelly

theory based on free radical and radiation chemistry . Journal of Gerontology, 11 ( 1 ), 298 – 300 . doi: 10.1093/geronj/11.3.298 Hay , M.E. , Connelly , D.M. , & Kinsella , E.A. ( 2016 ). Embodiment and aging in contemporary physiotherapy . Physiotherapy Theory and Practice, 32 ( 4 ), 241