measures would be negatively related to initial T levels. As a secondary aim, we investigated other indicators of physical function and blood hematology, but no firm hypotheses were made regarding these outcomes. Methods Subjects A total of 16 male climbers with a mean (± SD ) age of 35.4 ±7.3 years
Blair Crewther, Konrad Witek, Paweł Draga, Piotr Zmijewski and Zbigniew Obmiński
Javier T. Gonzalez, Martin J. Barwood, Stuart Goodall, Kevin Thomas and Glyn Howatson
Unaccustomed eccentric exercise using large muscle groups elicits soreness, decrements in physical function and impairs markers of whole-body insulin sensitivity; although these effects are attenuated with a repeated exposure. Eccentric exercise of a small muscle group (elbow flexors) displays similar soreness and damage profiles in response to repeated exposure. However, it is unknown whether damage to small muscle groups impacts upon whole-body insulin sensitivity. This pilot investigation aimed to characterize whole-body insulin sensitivity in response to repeated bouts of eccentric exercise of the elbow flexors. Nine healthy males completed two bouts of eccentric exercise separated by 2 weeks. Insulin resistance (updated homeostasis model of insulin resistance, HOMA2-IR) and muscle damage profiles (soreness and physical function) were assessed before, and 48 h after exercise. Matsuda insulin sensitivity indices (ISIMatsuda) were also determined in 6 participants at the same time points as HOMA2-IR. Soreness was elevated, and physical function impaired, by both bouts of exercise (both p < .05) but to a lesser extent following bout 2 (time x bout interaction, p < .05). Eccentric exercise decreased ISIMatsuda after the first but not the second bout of eccentric exercise (time x bout interaction p < .05). Eccentric exercise performed with an isolated upper limb impairs whole-body insulin sensitivity after the first, but not the second, bout.
Patrick J. O’Connor, Amanda L. Caravalho, Eric C. Freese and Kirk J. Cureton
Compounds found in the skins of grapes, including catechins, quercetin, and resveratrol, have been added to the diet of rodents and improved run time to exhaustion, fitness, and skeletal-muscle mitochondrial function. It is unknown if such effects occur in humans. The purpose of this experiment was to investigate whether 6 wk of daily grape consumption influenced maximal oxygen uptake (VO2max), work capacity, mood, perceived health status, inflammation, pain, and arm-function responses to a mild eccentric-exercise-induced arm-muscle injury. Forty recreationally active young adults were randomly assigned to consume a grape or placebo drink for 45 consecutive days. Before and after 42 d of supplementation, assessments were made of treadmill-running VO2max, work capacity (treadmill performance time), mood (Profile of Mood States), and perceived health status (SF-36 Health Survey). The day after posttreatment treadmill tests were completed, 18 high-intensity eccentric actions of the nondominant elbow flexors were performed. Arm-muscle inflammation, pain, and function (isometric strength and range of motion) were measured before and on 2 consecutive days after the eccentric exercise. Mixed-model ANOVA showed no significant effect of grape consumption on any of the outcomes. Six weeks of supplemental grape consumption by recreationally active young adults has no effect on VO2max, work capacity, mood, perceived health status, inflammation, pain, or physical-function responses to a mild injury induced by eccentric exercise.
Leyre Gravina, Frankie F. Brown, Lee Alexander, James Dick, Gordon Bell, Oliver C. Witard and Stuart D.R. Galloway
Omega-3 fatty acid (n-3 FA) supplementation could promote adaptation to soccer-specific training. We examined the impact of a 4-week period of n-3 FA supplementation during training on adaptations in 1RM knee extensor strength, 20-m sprint speed, vertical jump power, and anaerobic endurance capacity (Yo-Yo test) in competitive soccer players. Twenty six soccer players were randomly assigned to one of two groups: n-3 FA supplementation (n-3 FA; n = 13) or placebo (n = 13). Both groups performed two experimental trial days. Assessments of physical function and respiratory function were conducted pre (PRE) and post (POST) supplementation. Training session intensity, competitive games and nutritional intake were monitored during the 4-week period. No differences were observed in respiratory measurements (FEV1, FVC) between groups. No main effect of treatment was observed for 1RM knee extensor strength, explosive leg power, or 20 m sprint performance, but strength improved as a result of the training period in both groups (p < .05). Yo-Yo test distance improved with training in the n-3 FA group only (p < .01). The mean difference (95% CI) in Yo-Yo test distance completed from PRE to POST was 203 (66–340) m for n-3 FA, and 62 (-94–217) m for placebo, with a moderate effect size (Cohen’s d of 0.52). We conclude that 4 weeks of n-3 FA supplementation does not improve strength, power or speed assessments in competitive soccer players. However, the increase in anaerobic endurance capacity evident only in the n-3 FA treatment group suggests an interaction that requires further study.
Sonsoles Hernández-Sánchez, Pedro L. Valenzuela, Javier S. Morales, Juan J. Carrero, Alejandro Lucia and Jonatan R. Ruiz
and medical monitoring—as a complementary tool to improve physical function and quality of life among kidney transplant patients. Acknowledgments Hernández-Sánchez and Valenzuela contributed equally to this work. This work was supported by the University of Alcalá (grant number FPI2016 to P
Edgar J. Gallardo and Andrew R. Coggan
products. Previous studies of higher doses of NO 2 − , that is, ∼2 to ∼4 mmol, provided in the form of sodium salt, have demonstrated improvements in various measures of physical function in older individuals ( Justice et al., 2015 ). It is not known, however, whether the smaller amount found in the
Francesco Campa, Catarina N. Matias, Elisabetta Marini, Steven B. Heymsfield, Stefania Toselli, Luís B. Sardinha and Analiza M. Silva
In sports, as well as in daily life, hydration status plays an important role, as hypohydration and fluid accumulation may affect physical function, cognitive performance, and health status. 1 – 3 Although laboratory clinical tests are typically preferred over signs and symptoms for detecting
Kelly Pritchett, Robert C. Pritchett, Lauren Stark, Elizabeth Broad and Melissa LaCroix
vitamin D with physical function in people with chronic spinal cord injury . Archives of Physical Medicine and Rehabilitation, 97 ( 5 ), 726 – 732 . PubMed ID: 26805770 doi:10.1016/j.apmr.2016.01.002 10.1016/j.apmr.2016.01.002 Barker , T. , Schneider , E. , Dixon , B. , Henriksen , V
Nick Dobbin, Jamie Highton, Samantha Louise Moss and Craig Twist
: 15903382 15903382 18. Waldron M , Gray A , Worsfold P , Twist C . The reliability of functional movement screening and in-season changes in physical function among elite rugby league players . J Strength Cond Res . 2016 ; 30 ( 4 ): 910 – 918 . PubMed ID: 27003450 doi:10.1519/JSC
Sarah J. Willis, Grégoire P. Millet and Fabio Borrani
blood flow on thigh muscle volume and VO 2 max in young men . J Sports Sci Med . 2010 ; 9 ( 3 ): 452 – 458 . PubMed ID: 24149640 24149640 12. Clarkson MJ , Conway L , Warmington SA . Blood flow restriction walking and physical function in older adults: a randomized control trial . J Sci Med