Compared with their physically active peers, overweight sedentary postmenopausal women demonstrate impaired vascular endothelial function (VEF), substantially increasing the risk for cardiovascular disease (CVD). Habitual exercise is associated with improved VEF and reduced CVD risk. The purpose of this study was to compare brachial artery flow mediated dilation (FMD), a measure of VEF, in overweight, postmenopausal women who were physically active (EX: n = 17, BMI: 29.3 ± 3.11 kg/m2) or sedentary (CON: n = 8, BMI: 30.3 ± 3.6 kg/m2). Anthropomorphic measures were similar in both groups (P > .05). FMD was significantly greater in EX (10.24 ± 2.36%) versus CON (6.60 ± 2.18%) (P < .002). FMD was not significantly correlated with estimated VO2max (EX: r = .17, P = .52; CON: r = .20, P = .60) but was negatively associated with percent body fat in EX group (EX: r = -.48, P = .05; CON: r = .41, P = .31). These results are consistent with the positive effects of habitual exercise on VEF in overweight postmenopausal women.
Kate Sanders, Carl M. Maresh, Kevin D. Ballard, Brent C. Creighton, J. Luke Pryor, William J. Kraemer, Jeff S. Volek and Jeff M. Anderson
Joowon Lee, Baojiang Chen, Harold W. Kohl III, Carolyn E. Barlow, Chong do Lee, Nina B. Radford, Laura F. DeFina and Kelley P. Gabriel
) a decrease of blood pressure ( Buse et al., 2007 ), and (e) an improvement of vascular endothelial function through an increase of nitric oxide bioavailability ( Green et al., 2003 ). Thus, it appears that PA favorably affects an extensive range of cardiovascular risk factors, and this change in the
Namkee G. Choi, Diana M. DiNitto, John E. Sullivan and Bryan Y. Choi
older adults with self-reported diabetes, 2000–2009 . Preventing Chronic Disease: Public Health Research, Practice, and Policy, 9, E89 . Lee , J.H. , Lee , R. , Hwang , M.H. , Hamilton , M.T. , & Park , Y. ( 2018 ). The effects of exercise on vascular endothelial function in type 2
Declan Ryan, Jorgen Wullems, Georgina Stebbings, Christopher Morse, Claire Stewart and Gladys Onambele-Pearson
Services and Public Safety . Physical Activity Guidelines for Older Adults (65+ Years) . London, UK : Department of Health Social Services and Public Safety ; 2011 . 4. Pahkala K , Heinonen OJ , Simell O , et al . Association of physical activity with vascular endothelial function and intima