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C. William Balke, Gloria H. Umberger, and Carl G. Mattacola

The postgenomic era and heightened public expectations for tangible improvements in the public health have stimulated a complete transformation of the nation's biomedical research enterprise. The National Institutes of Health (NIH) “Roadmap for Medical Research” has catalyzed this transformation. The NIH roadmap consists of several interrelated initiatives, of which the Clinical and Translational Science Award (CTSA) program is the most relevant for rehabilitation specialists. This article reviews the evolution of this transformation and highlights the unprecedented opportunities the CTSA program provides rehabilitation specialists to play leadership roles in improving the clinical care of their patients.

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Thomas H. Kelly and Carl G. Mattacola


The National Institutes of Health's Clinical and Translational Science Award initiative is designed to establish and promote academic centers of clinical and translational science (CTS) that are empowered to train and advance multi- and interdisciplinary investigators and research teams to apply new scientific knowledge and techniques to enhance patient care. Among the key components of a full-service center for CTS is an educational platform to support research training in CTS. Educational objectives and resources available to support the career development of the clinical and translational scientists, including clinical research education, mentored research training, and career development support, are described.


The purpose of the article is to provide an overview of the CTS educational model so that rehabilitation specialists can become more aware of potential resources that are available and become more involved in the delivery and initiation of the CTS model in their own workplace. Rehabilitation clinicians and scientists are well positioned to play important leadership roles in advancing the academic mission of CTS. Rigorous academic training in rehabilitation science serves as an effective foundation for supporting the translation of basic scientific discovery into improved health care. Rehabilitation professionals are immersed in patient care, familiar with interdisciplinary health care delivery, and skilled at working with multiple health care professionals.


The NIH Clinical and Translational Science Award initiative is an excellent opportunity to advance the academic development of rehabilitation scientists.

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Kerem Shuval, Liora Sahar, Kelley Pettee Gabriel, Gregory Knell, Galit Weinstein, Tal Gafni Gal, Felipe Lobelo, and Loretta DiPietro

should attempt to examine this relationship in larger, more representative samples, using a prospective design. Acknowledgments The present study did not receive financial support. The original RADI study was supported in part by grant UL1 RR024982 from the Clinical and Translational Science Award (CTSA

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Rachel R. Kleis, Janet E. Simon, Michael Turner, Luzita I. Vela, Abbey C. Thomas, and Phillip A. Gribble

Health as part of the Clinical and Translational Science Award (CTSA) program. Individuals interested in the study were emailed a link to the survey (Research Suite, Qualtrics, LLC, Provo, UT) between April 2015 and March 2016. To remove the confounding effect that previous ankle injuries may have on

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Stefanie N. Foster, Michael D. Harris, Mary K. Hastings, Michael J. Mueller, Gretchen B. Salsich, and Marcie Harris-Hayes

in Physical Therapy at Washington University School of Medicine, Clinical and Translational Science Award (CTSA). The authors certify that they have no affiliations with or financial involvement in any organization or entity with a direct financial interest in the subject matter or materials

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Vera K. Tsenkova, Chioun Lee, and Jennifer Morozink Boylan

Research Network on Successful Midlife Development. Data collection was supported by the following grants: M01-RR023942 (Georgetown) and M01-RR00865 (UCLA) from the General Clinical Research Centers Program, and 1UL1RR025011 (UW) from the Clinical and Translational Science Award (CTSA) program of the