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Hala Youssef, Carole Groussard, Sophie Lemoine-Morel, Christophe Jacob, Elie Moussa, Abdallah Fazah, Jean-Claude Pineau, Joel Pincemail, Josiane Cillard, and Arlette Delamarche

This study aimed to determine whether aerobic training could reduce lipid peroxidation and inflammation at rest and after maximal exhaustive exercise in overweight/obese adolescent girls. Thirty-nine adolescent girls (14-19 years old) were classified as nonobese or overweight/obese and then randomly assigned to either the nontrained or trained group (12-week multivariate aerobic training program). Measurements at the beginning of the experiment and at 3 months consisted of body composition, aerobic fitness (VO2peak) and the following blood assays: pre- and postexercise lipid peroxidation (15F2a-isoprostanes [F2-Isop], lipid hydroperoxide [ROOH], oxidized LDL [ox-LDL]) and inflammation (myeloperoxidase [MPO]) markers. In the overweight/obese group, the training program significantly increased their fat-free mass (FFM) and decreased their percentage of fat mass (%FM) and hip circumference but did not modify their VO2peak. Conversely, in the nontrained overweight/obese group, weight and %FM increased, and VO2peak decreased, during the same period. Training also prevented exercise-induced lipid peroxidation and/or inflammation in overweight/obese girls (F2-Isop, ROOH, ox-LDL, MPO). In addition, in the trained overweight/obese group, exercise-induced changes in ROOH, ox-LDL and F2-Isop were correlated with improvements in anthropometric parameters (waist-to-hip ratio, %FM and FFM). In conclusion aerobic training increased tolerance to exercise-induced oxidative stress in overweight/obese adolescent girls partly as a result of improved body composition.

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Luana Siqueira Andrade, Stephanie Santana Pinto, Mariana Ribeiro Silva, Paula Carolini Campelo, Samara Nickel Rodrigues, Mariana Borba Gomes, Vitor Lima Krüger, Graciele Ferreira de Ferreira, and Cristine Lima Alberton

after water-based training programs, whose purpose is to assess the interference between gait and cognition. 28 A recent study suggests that a water-based aerobic training program may present multicomponent characteristics that provide adaptations in several physical fitness parameters in sedentary

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Elizabeth F. Teel, Stephen W. Marshall, L. Gregory Appelbaum, Claudio L. Battaglini, Kevin A. Carneiro, Kevin M. Guskiewicz, Johna K. Register-Mihalik, and Jason P. Mihalik

without access to athletic trainers. The purpose of this phase 1 clinical trial was to establish the safety, feasibility, and adherence of an aerobic training program in healthy, recreationally active university students. We hypothesized that ACTIVE training would be safe and feasible in this cohort and

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Alireza Paahoo, Vahid Tadibi, and Nasser Behpoor

). Therefore, the aim of this study was to evaluate the effects of two 12-week HIIT or continuous aerobic training protocols on the ratio of anti-atherosclerotic to pre-atherosclerotic components, levels of inflammatory markers, and lipid profile in children with overweight/obesity. Methods Participants Forty

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Ragab K. Elnaggar, Mohammed A. Shendy, and Mahmoud S. Elfakharany

% higher risk of developing new-onset of asthma ( 26 ). Evidence exists that physical activity programs can reduce bronchospasm, improve respiratory capacity and physical fitness, and reduce the risk of asthma exacerbation ( 9 , 38 ). Aerobic training has been proposed as adjuvant therapy in the treatment

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Karla A. Kubitz and Daniel M. Landers

This study examined the effects of an 8-week aerobic training program on cardiovascular responses to mental stress. Dependent variables included electrocardiographic activity, blood pressure, electroencephalographic (EEG) activity, state anxiety, and state anger. Quantification of indicators of sympathetic, parasympathetic, and central nervous system activity (i.e., respiratory sinus arrhythmia, T-wave amplitude, and EEG activity, respectively) allowed examination of possible underlying mechanisms. Subjects (n = 24) were randomly assigned to experimental (training) and control (no training) conditions. Pre- and posttesting examined cardiorespiratory fitness and responses to mental stress (i.e., Stroop and mental arithmetic tasks). MANOVAs identified a significant effect on cardiorespiratory fitness, heart rate, respiratory sinus arrhythmia, and EEG alpha laterality. The results appear consistent with the hypothesis that enhanced parasympathetic nervous system activity and decreased central nervous system laterality serve as mechanisms underlying certain aerobic training effects.

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Dale I. Lovell, Ross Cuneo, and Greg C. Gass

This study examined the effect of aerobic training on leg strength, power, and muscle mass in previously sedentary, healthy older men (70–80 yr). Training consisted of 30–45 min of cycle ergometry at 50–70% maximal oxygen consumption (VO2max), 3 times weekly for 16 wk, then 4 wk detraining, or assignment to a nontraining control group (n = 12 both groups). Training increased leg strength, leg power, upper leg muscle mass, and VO2max above pretraining values (21%, 12%, 4%, and 15%, respectively; p < .05). However, all gains were lost after detraining, except for some gain in VO2max. This suggests that cycle ergometry is sufficient stimulus to improve neuromuscular function in older men, but gains are quickly lost with detraining. For the older population cycle ergometry provides the means to not only increase aerobic fitness but also increase leg strength and power and upper leg muscle mass. However, during periods of inactivity neuromuscular gains are quickly lost.

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Francisco J. Ordonez, Gabriel Fornieles-Gonzalez, Alejandra Camacho, Miguel A. Rosety, Ignacio Rosety, Antonio J. Diaz, and Manuel Rosety-Rodriguez

Recent studies have reported that obese young people with Down syndrome suffer from low-grade systemic inflammation. Whereas this condition may be improved in the general population by regular exercise, the problem has received no attention in the case of people with intellectual disability. Therefore, the authors’ aim was to assess the influence of aerobic training on plasma adipokines in obese women with Down syndrome. Twenty obese young women with Down syndrome volunteered for this study, 11 of whom were randomly assigned to a 10-wk aerobic-training program. They attended 3 sessions/wk, which consisted of warm-up exercises followed by the main activity on a treadmill (30–40 min) at a work intensity of 55–65% of peak heart rate and ended with a cooling-down period. The control group included 9 women with Down syndrome matched for age, sex, and body-mass index. Fat-mass percentage and distribution were measured, and plasma adipokine levels (leptin and adiponectin) were assessed. In addition, each participant performed a maximal graded continuous treadmill exercise test. These parameters were assessed pre- and postintervention. Aerobic training produced a significant increase in participants’ maximal oxygen uptake (20.2 ± 5.8 vs.23.7 ± 6.3 ml · kg−1 · min−1; p < .001), and plasma leptin levels were significantly reduced in the intervention group (54.2 ± 6.7 vs.45.7 ± 6.1 ng/ml; p = .026). Further significant correlations between plasma leptin and indices of obesity were found. In contrast, no significant changes were found in adiponectin levels (p > .05). None of the tested parameters changed in the control group. In conclusion, a 10-week training program reduced leptin levels in obese young women with Down syndrome.

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Yara Fidelix, Mara C. Lofrano-Prado, Leonardo S. Fortes, James O. Hill, Ann E. Caldwell, João P. Botero, and Wagner L. do Prado

Intervention The intervention consisted of clinical, nutritional, and psychological counseling and supervised aerobic training for 24 weeks, as previously described. 17 , 18 Clinical Counseling Medical follow-up was performed once a month by an endocrinologist. The session included a physical examination to

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Khaled Trabelsi, Kais el Abed, Stephen R. Stannard, Kamel Jammoussi, Khaled M. Zeghal, and Ahmed Hakim

The aim of this study was to evaluate the effects of aerobic training in a fasted versus a fed state during Ramadan on body composition and metabolic parameters in physically active men. Nineteen men were allocated to 2 groups: 10 practicing aerobic training in a fasted state (FAST) and 9 training in an acutely fed state (FED) during Ramadan. All subjects visited the laboratory for a total of 4 sessions on the following occasions: 3 days before Ramadan (Bef-R), the 15th day of Ramadan; the 29th day of Ramadan (End-R), and 21 days after Ramadan. During each session, subjects underwent anthropometric measurement, completed a dietary questionnaire, and provided fasting blood and urine samples. Body weight decreased in FAST and FED by 1.9% (p < .001) and 2.6% (p = .046), respectively. Body fat percentage decreased only in FAST by 6.2% (p = .016). FAST experienced an increase in the following parameters from Bef-R to End-R: urine specific gravity (0.64%, p = .012), urea (8.7%, p < .001), creatinine (7.5%, p < .001), uric acid (12.7%, p < .001), sodium (1.9%, p = .003), chloride (2.6%, p < .001), and high-density lipoprotein cholesterol (27.3%, p < .001). Of these parameters, only creatinine increased (5.8%, p = .004) in FED. Creatinine clearance values of FAST decreased by 8.9% (p < .001) and by 7.6% in FED (p = .01) from Bef-R to End-R. The authors conclude that aerobic training in a fasted state lowers body weight and body fat percentage. In contrast, fed aerobic training decreases only body weight. In addition, Ramadan fasting induced change in some metabolic parameters in FAST, but these changes were absent in FED.