Sirtuin 3 enzyme (SIRT3) is involved in the regulation of mitochondrial energy homeostasis by activating Peroxisome proliferator-activated receptor-gamma coactivator (PGC-1α). Murine models have shown that the protein SIRT3 was modified by exercise and diet, however, the effect of exercise without diet in humans has not been examined. Propose of this paper was to analyze the effect of aerobic training on SIRT3 and PGC-1α in skeletal muscle of overweight adolescents without change in caloric intake. Fourteen overweight or obese male adolescents (15.5 ± 0.8 years) trained 3 days-week/50 min x session, at 70-80% of maximal heart rate for 12 weeks. Anthropometrics and skeletal muscle biopsies from the vastus lateralis were taken before and after the exercise program to measure adiposity, SIRT3, and PGC-1α proteins. Peak aerobic capacity (VO2peak) was estimated before and after training. The participants did not change their eating habits during the intervention. SIRT3 (1.05 ± 0.11 vs. 1.25 ± 0.14 AU, p = .014) and PGC-1a (1.06 ± 0.15 V s 1.39 ± 0.20 AU, p = .009) increased. Fat percentage and waist circumference decreased (p < .05). VO2peak increased after training (p < .001). There was a significant association between SIRT3 and PGC-1α after training program. These data suggest that aerobic training increased SIRT3 and PGC-1a expression levels in sedentary, overweight, or obese adolescents.
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Aerobic Training Increases Expression Levels of SIRT3 and PGC-1α in Skeletal Muscle of Overweight Adolescents Without Change in Caloric Intake
Katya Vargas-Ortiz, Victoriano Perez-Vazquez, Francisco J. Diaz-Cisneros, Arturo Figueroa, Lizbeth M. Jiménez-Flores, Gustavo Rodriguez-DelaRosa, and Maciste H. Macias
U.S. Older Adults’ Participation in Balance Activities
Eric T. Hyde, John D. Omura, Tiffany J. Chen, David R. Brown, Janet E. Fulton, and Susan A. Carlson
and Human Services, 2018 ). The Physical Activity Guidelines for Americans, second edition ( Guidelines) recommends that all adults (including older adults) achieve at least 150 min/week of moderate-intensity aerobic physical activity, at least 75 min/week of vigorous-intensity aerobic physical
The Physiological Assessment and Analysis of the Physical Demand of Riding a Snowmobile
Tania Pereira, John Durocher, and Jamie Burr
exercise intensity over the duration of the activity and could include more vigorous bouts of activity within a ride. For example, oxygen consumption while horseback riding was measured to range from 40% to 80% of a rider’s maximal aerobic capacity over the course of a single ride in female recreational
The Development of Fast, Fit, and Fatigue Resistant Youth Field and Court Sport Athletes: A Narrative Review
Joey C. Eisenmann, Jason Hettler, and Kevin Till
events relies on the cardiorespiratory system and oxidative capacities of skeletal muscle to sustain a significant portion of the maximal aerobic speed (MAS). Aside from these hallmark speed and endurance events, other sports (nonswimming and noncycling) that depend on bipedal locomotion, particularly
PACER Performance of Children Aged 11–14 With Attention-Deficit Hyperactive Disorder
Timothy Martinson, Stephen A. Butterfield, Craig A. Mason, Shihfen Tu, Robert A. Lehnhard, and Christopher J. Nightingale
Aerobic capacity is widely accepted as the single best indicator of physical fitness and overall cardiovascular health in adolescents ( 2 ). Poor cardiovascular health and obesity in children are associated with hyperlipidemia, type II diabetes, hypertension, coronary artery disease, stroke, sleep
Awareness and Knowledge of the Physical Activity Guidelines for Americans, 2nd Edition
Tiffany J. Chen, Geoffrey P. Whitfield, Kathleen B. Watson, Janet E. Fulton, Emily N. Ussery, Eric T. Hyde, and Ken Rose
The Physical Activity Guidelines for Americans, second edition (Guidelines), released in 2018, recommends a similar guideline for adults as in the 2008 Physical Activity Guidelines for Americans (2008 Guidelines) 1 of at least 150 minutes of moderate-intensity aerobic physical activity, 75
Stretching is Superior to Brisk Walking for Reducing Blood Pressure in People With High–Normal Blood Pressure or Stage I Hypertension
Jongbum Ko, Dalton Deprez, Keely Shaw, Jane Alcorn, Thomas Hadjistavropoulos, Corey Tomczak, Heather Foulds, and Philip D. Chilibeck
evidence that increasing physical activity can reduce blood pressure in people with either normal (<140/90 mm Hg) or high blood pressure. 5 The American College of Sports Medicine position statement recommends that one should perform 30 minutes of continuous or accumulated mainly aerobic physical activity
The Self-Paced Submaximal Run Test: Associations With the Graded Exercise Test and Reliability
Hannah F. Sangan, James G. Hopker, Glen Davison, and Shaun J. McLaren
The frequent and reliable monitoring of an individual’s responses to endurance training is an important component in the management of appropriate training stress and recovery. 1 Endurance performance is determined by the level of aerobic metabolism that can be maintained during a race (performance
The Effects of a 12-Week Combined Exercise Training Program on Arterial Stiffness, Vasoactive Substances, Inflammatory Markers, Metabolic Profile, and Body Composition in Obese Adolescent Girls
Alexei Wong, Marcos A. Sanchez-Gonzalez, Won-Mok Son, Yi-Sub Kwak, and Song-Young Park
has been suggested as a nonpharmacological treatment to decrease excess adipose tissue while improving cardiovascular function in both young and old individuals ( 15 , 45 ). Although the effectiveness of aerobic exercise for decreasing fat mass and IR in obese pediatric and adults populations is well
Energetic Profiles of the Yo-Yo Intermittent Recovery Tests 1 and 2
Sebastian Kaufmann, Olaf Hoos, Timo Kuehl, Thomas Tietz, Dominik Reim, Kai Fehske, Richard Latzel, and Ralph Beneke
-Yo Intermittent Recovery Tests 1 and 2 (YYIR1 and YYIR2) are well established tests, applied in a variety of team sports, 9 and both have been shown to detect changes in intermittent running performance over certain training periods. 11 YYIR1 and YYIR2 are highly demanding for the aerobic energy system and
