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Michal Botek, Jakub Krejčí, Andrew J. McKune and Barbora Sládečková

cellular redox balance, 4 and has a stimulating effect on mitochondrial oxidative phosphorylation. 5 Supplementation with hydrogen-rich water (HRW) before exercise has been shown to improve lactate, ventilatory, and perceptual response 6 as well as have an antifatigue effect, particularly in endurance

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Takeshi Kokubo, Yuta Komano, Ryohei Tsuji, Daisuke Fujiwara, Toshio Fujii and Osamu Kanauchi

increase in voluntary locomotor activity in the LC-Plasma group, suggesting that LC-Plasma may have an anti-fatigue effect. Similar observations have been previously reported in athletes; thus, we had confirmed this effect in both preclinical and clinical trial ( Komano et al., 2018 ). The levels of TGF