We studied the effect of physical inactivity and subsequent retraining on cardiovascular risk factors in 17 young (Y; 23.4 ± 0.5 years) and 15 older adult (O; 68.1 ± 1.1 years) men who underwent 14 days of one leg immobilization followed by six weeks of training. Body weight remained unchanged. Daily physical activity decreased by 31 ± 9% (Y) and 37 ± 9% (O) (p < .001). Maximal oxygen uptake decreased with inactivity (Y) and always increased with training. Visceral fat mass decreased (p < .05) with training. Concentrations of lipids in blood were always highest in the older adults. FFA and glycerol increased with reduced activity (p < .05), but reverted with training. Training resulted in increases in HDL-C (p < .05) and a decrease in LDL-C and TC:HDL-C ratio (p < .05). A minor reduction in daily physical activity for two weeks increased blood lipids in both young and older men. Six weeks of training improved blood lipids along with loss of visceral fat.
Jesper Nørregaard, Martin Gram, Andreas Vigelsø, Caroline Wiuff, Anja Birk Kuhlman, Jørn Wulff Helge and Flemming Dela
Paul J. Collings, Diane Farrar, Joanna Gibson, Jane West, Sally E. Barber and John Wright
higher concentration of high-density lipoprotein cholesterol (HDL-c), 8 established precursors of CVD. 9 It is unknown if maternal physical activity confers similar benefits, that is a more favorable blood lipid profile, to the developing fetus. This is important to investigate, as cord blood lipid
Neil Armstrong and Bruce Simons-Morton
A computer search was complemented with an extensive hand search of bibliographies of located studies. All controlled trials, studies of trained versus untrained subjects, and reports of habitual physical activity in relation to lipid profile were analyzed and tabulated. The high-risk population was represented by controlled trials that reported relevant data. More convincing evidence for a beneficial effect of physical activity on blood lipids is apparent in cross-sectional studies. The results of longitudinal studies are unimpressive, but the studies are generally lacking in rigor. Empirical dose-response data relating the effects of physical activity to blood lipids in adolescents are nonexistent. Recommendations for an appropriate exercise prescription must therefore be based upon adult data and expert opinion. Emphasis should be placed upon promoting an increase in the amount of adolescents’ habitual physical activity.
Michael L. Mestek, John C. Garner, Eric P. Plaisance, James Kyle Taylor, Sofiya Alhassan and Peter W. Grandjean
The purpose of this study was to compare blood lipid responses to continuous versus accumulated exercise. Nine participants completed the following conditions on separate occasions by treadmill walking/jogging at 70% of VO2max : 1) one 500-kcal session and 2) three 167 kcal sessions. Total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) concentrations were measured from serum samples obtained 24 h prior to and 24 and 48 h after exercise. All blood lipid responses were analyzed in 2 (condition) × 3 (time) repeated measures ANOVAs. HDL-C increased by 7 mg/dL over baseline at 48 h post-exercise with three accumulated sessions versus 2 mg/dL with continuous exercise (P < 0.05). Triglyceride concentrations were unchanged in both conditions. These findings suggest that three smaller bouts accumulated on the same day may have a modestly greater effect for achieving transient increases in HDL-C compared to a continuous bout of similar caloric expenditure.
Daniel L. Blessing, Robert E. Keith, Henry N. Williford, Marjean E. Blessing and Jeff A. Barksdale
The purpose of this study was to determine the effects of an endurance training program on blood lipids and lipoproteins in adolescents. Fifteen males and 10 females, ages 13 to 18 years, underwent pretest evaluations, including physical measurements, nutritional intake, physical working capacity (PWC), and fasting serum lipid and lipoprotein levels. Physical conditioning consisted of a 16-week progressive endurance training (ET) program 40 min·day1 three times per week. Twenty-five males and females matched for age, sex, and race served as controls. Following the conditioning program, the ET group had a significant increase (p < .05) in PWC and a significant decrease (p < .05) in sum of skinfolds and resting heart rate. A significant decrease (p < .05) was also noted for total cholesterol (TC) and the ratio of TC to high density lipoprotein cholesterol (HDL-C) with a significant increase (p < .05) in HDL-C. No differences were found for the control group. The results suggest that 16 weeks of endurance training favorably improves blood lipid profiles in adolescents.
Evelien Mertens, Peter Clarys, Johan Lefevre, Ruben Charlier, Sara Knaeps and Benedicte Deforche
Longitudinal evidence concerning the association between cardiorespiratory fitness (CRF) and blood lipids and between anthropometric parameters (ANTP) and blood lipids is limited. This study aimed to investigate the association between changes in CRF and ANTP and changes in blood lipids.
In 2002–2004 and 2012–2014, 652 participants were tested. CRF was measured as VO2peak using a maximal ergometer test. Waist circumference (WC) and Body Mass Index (BMI) were used as ANTP. Blood samples were analyzed for total cholesterol (TC), HDL cholesterol, LDL cholesterol and triglycerides. A linear regression analysis was performed to investigate associations between changes in CRF and ANTP and changes in blood lipids.
After adjustment a decrease in CRF was associated with an increase in triglycerides and a decrease in HDL cholesterol in men. An increase in WC was associated with an increase in TC, LDL cholesterol and ratio total/HDL cholesterol and a decrease in HDL cholesterol, while an increase in BMI was associated with an increase in ratio total/HDL cholesterol and a decrease in HDL cholesterol.
WC and BMI were more longitudinally associated with blood lipids compared with CRF. Improving ANTP can enhance the blood lipid profile, while CRF had only limited influence.
Ehsan Ghahramanloo, Adrian W. Midgley and David J. Bentley
There is little information regarding the effects of concurrent training (endurance and resistance training performed in the same overall regimen) on blood lipid profile in sedentary male subjects. This study compared the effects of 3 different 8-wk training programs [endurance training (ET), strength training (ST) and concurrent training (CT)] on blood lipid profile and body composition in untrained young men.
A total of 27 subjects were randomly allocated to an ET, ST or CT group which performed either progressive treadmill (ET), free weight (ST) or both the endurance and strength training requirements for 8 weeks.
High-density lipoprotein and low-density lipoprotein profiles significantly improved in the ET and CT groups (P < .01) but not in the ST group. Triglyceride and total cholesterol profiles significantly improved in all 3 training groups. Total fat mass significantly decreased in the ET and CT groups (P < .001) but not in the ST group, whereas fat free mass significantly increased in the ST and CT groups (P < .01) but not in the ET group.
These results indicate that CT can be used to simultaneously improve both the serum lipid profile and body composition of previously untrained, apparently health young men.
Peter Pagels, Anders Raustorp, Trevor Archer, Ulf Lidman and Marie Alricsson
Health organizations suggest that adults ought to engage in at least 30 minutes of moderate-intensity daily physical activity. This study investigated the effects of a 30-minute single daily bout of brisk walking upon risk factors for coronary heart disease with blood lipid profile in particular.
Thirty-three (25–45 y) adults, were randomly assigned into an exercise group (EG; n = 16, 9w) and a control group (CG; n = 17, 6w). The EG walked briskly 30 minutes daily during the 3-week test period. Compliance/adherence was maximal throughout the 3-week intervention due to stringent daily monitoring.
The EG showed a significant decrease in concentrations of low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) during the intervention period. A significant inverse correlation between Δ energy expenditure/day and Δ LDL-C (r = –0.39, P < .05) and an improvement in weight and BMI in the EG was found. Average steps during 30 minutes brisk walking bout was 3669 steps/bout generating a mean energy expenditure of 191 kcal/ bout.
The most unique findings were that daily single bouts of moderate-intensity physical activity for 30 minutes, during 3 weeks, induced favorable effects upon body weight, BMI, and blood concentration of LDL-C and TC in healthy adults.
Rochelle D. Kirwan, Lindsay K. Kordick, Shane McFarland, Denver Lancaster, Kristine Clark and Mary P. Miles
The purpose of this study was to determine the dietary, anthropometric, blood-lipid, and performance patterns of university-level American football players attempting to increase body mass during 8 wk of training.
Three-day diet records, body composition (DEXA scan), blood lipids, and performance measures were collected in redshirt football players (N = 15, age 18.5 ± 0.6 yr) early season and after 8 wk of in-season training.
There was an increase (p < .05) from early-season to postseason testing for reported energy (+45%), carbohydrate (+82%), and protein (+29%) intakes and no change in the intake of fat. Fat intake was 41% of energy at the early-season test and 32% of energy at the postseason test. Increases (p < .05 for all) in performance measures, lean mass (70.5 ± 7.7–71.8 ± 7.7 kg), fat mass (15.9 ± 6.2–17.3 ± 6.8 kg), plasma total cholesterol (193.5 ± 32.4–222.6 ± 40.0 mg/dl), and low-density lipoproteins (LDL; 92.7 ± 32.7–124.5 ± 34.7 mg/dl) were measured. No changes were measured in triglycerides, very-low-density lipoproteins, or high-density lipoproteins.
Increases in strength, power, speed, total body mass, muscle mass, and fat mass were measured. Cholesterol and LDL levels increased during the study to levels associated with higher risk for cardiovascular disease. It is possible that this is a temporary phenomenon, but it is cause for concern and an indication that dietary education to promote weight gain in a manner less likely to adversely affect the lipid profile is warranted.
James H. Rimmer, Dave Braddock and Glenn Fujiura
Little data exist on the comparison of blood lipids and percent body fat between Down Syndrome and non-DS adults with mental retardation (MR). The following study was undertaken to determine if there were physiological and biochemical differences between these two groups. Subjects included 294 non-DS adults with MR (162 males and 132 females) and 31 adults with Down Syndrome (21 males and 10 females). Level of mental retardation was similar for both groups (males/females, Down vs. non-DS). A two-factor ANOVA with a regression approach was used to analyze the data. Results of the study found that there were no significant differences between the Down Syndrome and non-DS subjects on total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, or percent body fat. The present study suggests that the composition of lipoproteins and storage of body fat are similar in Down Syndrome and non-DS adults with mental retardation, and that the risk for developing coronary heart disease appears to be the same for both groups.