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Bryan Saunders, Craig Sale, Roger C. Harris, and Caroline Sunderland


To determine whether gastrointestinal (GI) distress affects the ergogenicity of sodium bicarbonate and whether the degree of alkalemia or other metabolic responses is different between individuals who improve exercise capacity and those who do not.


Twenty-one men completed 2 cycling-capacity tests at 110% of maximum power output. Participants were supplemented with 0.3 g/kg body mass of either placebo (maltodextrin) or sodium bicarbonate (SB). Blood pH, bicarbonate, base excess, and lactate were determined at baseline, preexercise, immediately postexercise, and 5 min postexercise.


SB supplementation did not significantly increase total work done (TWD; P = .16, 46.8 · 9.1 vs 45.6 · 8.4 kJ, d = 0.14), although magnitude-based inferences suggested a 63% likelihood of a positive effect. When data were analyzed without 4 participants who experienced GI discomfort, TWD (P = .01) was significantly improved with SB. Immediately postexercise blood lactate was higher in SB for the individuals who improved but not for those who did not. There were also differences in the preexercise-to-postexercise change in blood pH, bicarbonate, and base excess between individuals who improved and those who did not.


SB improved high-intensity-cycling capacity but only with the exclusion of participants experiencing GI discomfort. Differences in blood responses suggest that SB may not be beneficial to all individuals. Magnitude-based inferences suggested that the exercise effects are unlikely to be negative; therefore, individuals should determine whether they respond well to SB supplementation before competition.

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Óscar Martínez de Quel, Ignacio Ara, Mikel Izquierdo, and Carlos Ayán

– 99 . 16117305 28. Ravier G , Dugue B , Grappe F , Rouillon JD . Maximal accumulated oxygen deficit and blood responses of ammonia, lactate and pH after anaerobic test: a comparison between international and national elite karate athletes. Int J Sports Med . 2006 ; 27 ( 10 ): 810 – 817

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Llion A. Roberts, Johnpaul Caia, Lachlan P. James, Tannath J. Scott, and Vincent G. Kelly

d (90% confidence interval range). * P  < .05, group mean change from Pre. Blood Responses Testosterone and cortisol changed during the trial (time main effects: P  < .0001) but were not influenced by recovery treatments (no condition or interaction effects). Testosterone did not change pre

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Rebecca L. Jones, Trent Stellingwerff, Paul Swinton, Guilherme Giannini Artioli, Bryan Saunders, and Craig Sale

blood bicarbonate reduced and lactate increased following the warm-up; blood responses occurred to a greater degree in the HI warm-up condition compared to the LI, and in SB compared to PLA (Figures  3 and 4 ). Blood bicarbonate was higher, and lactate lower, following 30-min recovery in SB than PLA

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Saowaluck Suntraluck, Hirofumi Tanaka, and Daroonwan Suksom

, Z. , Labial , L. , Iouciulescu , R. , … Malty , A.A. ( 2007 ). The effects of aging on the skin blood response to warm, cold, and contrast warm and cold baths . Physical and Occupational Therapy in Geriatrics, 25 ( 3 ), 19 – 33 . doi: 10.1080/J148v25n03_02 Quattrini , C. , Harris , N