of ability of kidney to clear plasma of nitrogenous wastes over a specific period. At present, it is regarded as the best way to examine kidney function. The estimated glomerular filtration rate (eGFR, in mL/min/1.73 m 2 ) was calculated from serum creatinine using the Chronic Kidney Disease
Dahai Yu, Ying Chen, Tao Chen, Yamei Cai, Rui Qin, Zhixin Jiang and Zhanzheng Zhao
Sungchul Lee, Sangyoon Lee, Seongryu Bae, Kazuhiro Harada, Songee Jung, Keitaro Makino and Hiroyuki Shimada
needing LTCI services. Figure 1 —Flowchart of respondents. eGFR = estimated glomerular filtration rate; MMSE = Mini-Mental State Examination; LTCI = long-term care insurance. Table 1 Baseline Characteristics of the Study Participants by Incident Disability ( n = 4,457) Variable Total ( n = 4
Marquis Hawkins, Anne B. Newman, Magdalena Madero, Kushang V. Patel, Michael G. Shlipak, Jennifer Cooper, Kirsten L. Johansen, Sankar D. Navaneethan, Ronald I. Shorr, Eleanor M. Simonsick and Linda F Fried
Physical activity (PA) may play a role in preserving kidney health. The purpose of this study was to determine if PA and sedentary behavior are associated with incident chronic kidney disease (CKD) and change in kidney function in older adults.
The Health, Aging, and Body Composition study is a prospective cohort of 3075 well-functioning older adults. PA and television watching was measured by self-report, and serum cystatin C was used to estimate glomerular filtration rate (eGFR). CKD was defined as an eGFR <60 ml/min/1.73m2. Rapid kidney function decline was defined as an annual loss in eGFR of >3ml/min/1.73m2. Discrete survival analysis was used to determine if baseline PA and television watching were related to 10-year cumulative incidence of CKD and rapid decline in kidney function.
Individuals who reported watching television >3 hours/day had a higher risk of incident CKD (HR 1.34; 95% CI, 1.09-1.65) and experiencing a rapid decline in kidney function (HR 1.26; 95% CI, 1.05-1.52) compared with individuals who watched television <2 hours/day. PA was not related to either outcome.
High levels of television watching are associated with declining kidney function; the mechanisms that underlie this association need further study.
Jieling Chen, Emily Joy Nicklett, Yaping He and Vivian W.Q. Lou
). Complete cystatin C and physical activity measures were available for 3,684 participants. An estimated glomerular filtration rate was calculated using the CKD-Epidemiology Collaboration cystatin C equation ( Inker et al., 2012 ). Sixty-two participants aged 44 years or younger and four participants with an
Yasuhiko Kubota, Alvaro Alonso, Amil M. Shah, Lin Y. Chen and Aaron R. Folsom
graduation, high school with graduation, vocational school, college with or without graduation, or graduate or professional school), alcohol drinking status (current, former, or never), height (in centimeters), estimated glomerular filtration rate (in milliliters per minute), electrocardiogram (ECG