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Dietary Intake and Gastrointestinal Integrity in Runners Undertaking High-Intensity Exercise in the Heat

Naroa Etxebarria, Nicole A. Beard, Maree Gleeson, Alice Wallett, Warren A. McDonald, Kate L. Pumpa, and David B. Pyne

for biomarkers, which represent GI permeability, included lipopolysaccharide (LPS), lipopolysaccharide-binding protein, and intestinal fatty-acid-binding protein (i-FABP). All biomarkers were analyzed in duplicate, as previously described ( Wallett et al., 2020 ). Statistical Analysis The descriptive

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Repeated-Sprint Exercise in the Heat Increases Indirect Markers of Gastrointestinal Damage in Well-Trained Team-Sport Athletes

Alice Wallett, Andrew McKune, David Pyne, David Bishop, Olivier Girard, Philo Saunders, and Julien Périard

associated with maximum rate of oxygen consumption, plasma intestinal fatty acid binding protein concentration ([I-FABP]), and GI permeability (as measured by the ratio of L-lactulose/rhamnose) increased by 72% and 59%, respectively, relative to rest ( Pugh et al., 2017 ). Similarly, running at 80% of best

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Running at Increasing Intensities in the Heat Induces Transient Gut Perturbations

Alice M. Wallett, Naroa Etxebarria, Nicole A. Beard, Philo U. Saunders, Marijke Welvaert, Julien D. Périard, Andrew J. McKune, and David B. Pyne

), an acute phase response protein that mediates the rise in LPS, and intestinal fatty acid–binding protein (I-FABP), an early GI-ischemia marker. 10 While there is evidence supporting the premise that heat stress mediates exercise-induced endotoxemia, specific GI responses to exercise in the heat at

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The Impact of a Short-Term Ketogenic Low-Carbohydrate High-Fat Diet on Biomarkers of Intestinal Epithelial Integrity and Gastrointestinal Symptoms

Alannah K.A. McKay, Alice M. Wallett, Andrew J. McKune, Julien D. Périard, Philo Saunders, Jamie Whitfield, Nicolin Tee, Ida A. Heikura, Megan L.R. Ross, Avish P. Sharma, Ricardo J.S. Costa, and Louise M. Burke

concentrations of intestinal fatty acid-binding protein (I-FABP), lipopolysaccharide-binding protein (LBP), and soluble CD14 (sCD14) were measured in duplicate using commercially available enzyme-linked immunosorbent assay kits (HK406, HK315, and HK320, respectively; Hycult Biotech). The intraassay coefficient

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Anthocyanin-Rich Blackcurrant Extract Preserves Gastrointestinal Barrier Permeability and Reduces Enterocyte Damage but Has No Effect on Microbial Translocation and Inflammation After Exertional Heat Stress

Ben J. Lee, Tessa R. Flood, Ania M. Hiles, Ella F. Walker, Lucy E.V. Wheeler, Kimberly M. Ashdown, Mark E.T. Willems, Rianne Costello, Luke D. Greisler, Phebe A. Romano, Garrett W. Hill, and Matthew R. Kuennen

(210 mg anthocyanins per day) on small intestinal permeability (dual sugar absorption test), plasma intestinal epithelial injury (serum intestinal fatty acid-binding protein [I-FABP]), microbial translocation (serum lipopolysaccharide-binding protein [LBP]), and soluble CD14 [sCD14]) in conjunction

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Amino Acid-Based Beverage Interventions Ameliorate Exercise-Induced Gastrointestinal Syndrome in Response to Exertional-Heat Stress: The Heat Exertion Amino Acid Technology (HEAAT) Study

Ricardo J.S. Costa, Kayla Henningsen, Stephanie K. Gaskell, Rebekah Alcock, Alice Mika, Christopher Rauch, Samuel N. Cheuvront, Phil Blazy, and Robert Kenefick

50 μl that was used to determine plasma osmolality (P Osmol ), in duplicate (CV: 1.0%), by freezepoint osmometry (Osmomat 030, Gonotec). Plasma concentrations of cortisol (DKO001, DiaMetra), intestinal fatty acid protein (I-FABP; HK406, Hycult Biotech), soluble CD14 (sCD14; HK320, Hycult Biotech

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The Impact of a Dairy Milk Recovery Beverage on Bacterially Stimulated Neutrophil Function and Gastrointestinal Tolerance in Response to Hypohydration Inducing Exercise Stress

Ricardo J.S. Costa, Vera Camões-Costa, Rhiannon M.J. Snipe, David Dixon, Isabella Russo, and Zoya Huschtscha

fatty acid binding protein (I-FABP) concentration ( Costa et al., 2019b ; Costa et al., 2017b ). In addition, exercise stress has the potential to reduce gastrointestinal transit and enterocyte cell activity through mesenteric and submucosal plexus deactivation linked with the natural stress response

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Abstracts From the 6th Annual Congress on Medicine & Science in Ultra-Endurance Sports, October 11–13, 2019, Cape Town, South Africa

SILVA. Blood samples were collected pre- and post-exercise to determine I-FABP, cortisol, and cytokine profiles. Markers of physiological and thermoregulatory strain, and gastrointestinal symptoms (GIS) were measured throughout. Correlations and β-diversity analysis between amplicon sequence variants

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Assessment of Exercise-Associated Gastrointestinal Perturbations in Research and Practical Settings: Methodological Concerns and Recommendations for Best Practice

Ricardo J.S. Costa, Pascale Young, Samantha K. Gill, Rhiannon M.J. Snipe, Stephanie Gaskell, Isabella Russo, and Louise M. Burke

standardize ( Pugh et al., 2019 ; Roberts et al., 2016 ; Zadow et al., 2021 ). Figure 2 —Exercise-associated disturbances to markers of gastrointestinal integrity, systemic responses, and GIS. Plasma (a) I-FABP, (b) sCD14, (c) LBP, (d) gram-negative bacterial endotoxin, (e) antiendotoxin IgM, (f

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The Effects of an Acute “Train-Low” Nutritional Protocol on Markers of Recovery Optimization in Endurance-Trained Male Athletes

Isabella Russo, Paul A. Della Gatta, Andrew Garnham, Judi Porter, Louise M. Burke, and Ricardo J.S. Costa

, intestinal fatty-acid-binding protein [I-FABP] and sCD14 enzyme-linked immunosorbent assay [ELISA], and multiplex system for systemic inflammatory profile) as previously reported. 6 , 15 , 22 The CVs for ELISAs were ≤6.1%, and for cytokine, profile multiplex was 16.0%. Breath samples (20 mL) were analyzed