This study aimed to determine whether aerobic training could reduce lipid peroxidation and inflammation at rest and after maximal exhaustive exercise in overweight/obese adolescent girls. Thirty-nine adolescent girls (14-19 years old) were classified as nonobese or overweight/obese and then randomly assigned to either the nontrained or trained group (12-week multivariate aerobic training program). Measurements at the beginning of the experiment and at 3 months consisted of body composition, aerobic fitness (VO2peak) and the following blood assays: pre- and postexercise lipid peroxidation (15F2a-isoprostanes [F2-Isop], lipid hydroperoxide [ROOH], oxidized LDL [ox-LDL]) and inflammation (myeloperoxidase [MPO]) markers. In the overweight/obese group, the training program significantly increased their fat-free mass (FFM) and decreased their percentage of fat mass (%FM) and hip circumference but did not modify their VO2peak. Conversely, in the nontrained overweight/obese group, weight and %FM increased, and VO2peak decreased, during the same period. Training also prevented exercise-induced lipid peroxidation and/or inflammation in overweight/obese girls (F2-Isop, ROOH, ox-LDL, MPO). In addition, in the trained overweight/obese group, exercise-induced changes in ROOH, ox-LDL and F2-Isop were correlated with improvements in anthropometric parameters (waist-to-hip ratio, %FM and FFM). In conclusion aerobic training increased tolerance to exercise-induced oxidative stress in overweight/obese adolescent girls partly as a result of improved body composition.
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Alannah K.A. McKay, Rachel McCormick, Nicolin Tee, and Peter Peeling
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Diana Keyhani, Bakhtyar Tartibian, Arezou Dabiri, and Ana Maria Botelho Teixeira
behavior, abnormal plasma lipids, increased blood pressure, changes in body fat distribution, reduced glucose tolerance, increased sympathetic tone, endothelial dysfunction, and vascular inflammation ( Rosano, Vitale, Marazzi, & Volterrani, 2007 ). Additionally, PMW are more likely to evolve CVD because
David C. Nieman, Francesca Ferrara, Alessandra Pecorelli, Brittany Woodby, Andrew T. Hoyle, Andrew Simonson, and Giuseppe Valacchi
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Henning T. Langer, Agata A. Mossakowski, Suraj Pathak, Mark Mascal, and Keith Baar
( Lang et al., 2003 ) and myofibrillar protein synthesis in humans following resistance-type exercise ( Parr et al., 2014 ). To determine whether acute treatment with CBD decreases inflammation and anabolic signaling following eccentric contractions, we measured the phosphorylation of mTORC1 targets
Rebecca Quinlan and Jessica A. Hill
studies have investigated the efficacy of TCJ following intermittent exercise, but these studies have yielded conflicting results. No benefits of TCJ on functional performance, markers of inflammation (interleukin 6, C-reactive protein [CRP]), or oxidative stress (uric acid) were demonstrated after water
Yijian Ding and Xi Xu
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Chantal A. Vella, Erin D. Michos, Dorothy D. Sears, Mary Cushman, Rachel B. Van Hollebeke, Michelle M. Wiest, and Matthew A. Allison
, cardiovascular disease risk factors, adiposity, and markers of inflammation. Methods Participants The Multi-Ethnic Study of Atherosclerosis (MESA) is a longitudinal cohort study of adults from 6 regions across the United States. The overall design of the MESA study has been published. 12 In brief, the cohort
