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Alex S. Ribeiro, Ademar Avelar, Witalo Kassiano, João Pedro Nunes, Brad J. Schoenfeld, Andreo F. Aguiar, Michele C.C. Trindade, Analiza M. Silva, Luís B. Sardinha and Edilson S. Cyrino

factor-1) and the expression of myogenic regulatory factors, resulting in enhanced satellite cells’ mitotic activities and differentiation into myonuclei ( Farshidfar et al., 2017 ). Moreover, Cr acts as an osmolyte, inducing an increase in intracellular water (ICW), which, in turn, may increase protein

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Francesco Campa, Catarina N. Matias, Elisabetta Marini, Steven B. Heymsfield, Stefania Toselli, Luís B. Sardinha and Analiza M. Silva

extracellular water (ECW) to intracellular water (ICW) ratio (ECW/ICW) 12 – 14 and may be used as a good tool for assessing the systemic efficiency exercise interventions and for looking at hydration status and cell functioning relevant for health and sports performance. 15 Classic BIVA has been applied in

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Alex S. Ribeiro, Matheus A. Nascimento, Brad J. Schoenfeld, João Pedro Nunes, Andreo F. Aguiar, Edilaine F. Cavalcante, Analiza M. Silva, Luís B. Sardinha, Steven J. Fleck and Edilson S. Cyrino

the square of height (m). Bioelectrical Impedance and Body Composition Measurements Spectral bioelectrical impedance equipment (Xitron Hydra, model 4200; Xitron Technologies, San Diego, CA) was used to estimate total body water (TBW), intracellular water (ICW), extracellular water, resistance ( R

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Vincent J. Dalbo, Michael D. Roberts, Scott E. Hassell, Jordan R. Moon and Chad M. Kerksick


This investigation examined the safety and efficacy of a silica-based mineral antioxidant complex (MAC) that has been suggested to influence body water and buffer lactate.


In a double-blind, randomized crossover design, male participants completed testing for 3 conditions: water only (baseline), rice flour (placebo), and MAC supplementation. Participants visited the laboratory on 5 occasions: familiarization, baseline, Testing Day 1, washout, and Testing Day 2. Baseline and Testing Days 1 and 2 consisted of fasting blood, pre- to postexercise body-water assessment and determination of VO2peak on a cycle ergometer. The supplementation protocols were separated by 1 wk and balanced to minimize an order effect.


No differences between conditions were found for heart rate, blood pressure, or serum-safety markers (p > .05). Before exercise there were no differences between conditions for total body water (TBW), intracellular water (ICW), or extracellular water (ECW). No significant interactive effects for supplementation and exercise were found for TBW, ICW, or ECW (p > .05). A time effect for TBW (p < .01) and ICW (p < .001) was present. Within-group changes in TBW occurred in the MAC condition, and within-group changes for ICW occurred in the MAC and placebo conditions. Ratings of perceived exertion and blood lactate increased (p < .05) with exercise. No significant effects were found for performance variables.


MAC supplementation had no impact on aerobic exercise performance and lactate response. Increases in TBW and ICW occurred after MAC consumption, but these changes appeared to have minimal physiological impact.

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. Hoyle * Andrew Simonson * Giuseppe Valacchi * 15 09 2020 1 11 2020 30 6 396 404 10.1123/ijsnem.2020-0084 ijsnem.2020-0084 Creatine Supplementation Does Not Influence the Ratio Between Intracellular Water and Skeletal Muscle Mass in Resistance-Trained Men Alex S. Ribeiro * Ademar Avelar * Witalo

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João Pedro Nunes, Alex S. Ribeiro, Analiza M. Silva, Brad J. Schoenfeld, Leandro dos Santos, Paolo M. Cunha, Matheus A. Nascimento, Crisieli M. Tomeleri, Hellen C.G. Nabuco, Melissa Antunes, Letícia T. Cyrino and Edilson S. Cyrino

, cell size, cellular hydration, and cell membrane permeability ( Norman et al., 2012 ). Therefore, considering the increases in intracellular water, total body water, and reactance after the intervention period, it can be speculated that RT induces metabolic stress, thus favoring the accumulation of

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Eric S. Rawson, Mary P. Miles and D. Enette Larson-Meyer

response to exercise via increased growth factor/gene expression, increased intracellular water; reduced symptoms of or enhanced recovery from muscle damaging exercise (e.g., DOMS); enhanced recovery from disuse, immobilization, or extreme inactivity such as after injury; improved cognitive processing

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Ronald J. Maughan, Louise M. Burke, Jiri Dvorak, D. Enette Larson-Meyer, Peter Peeling, Stuart M. Phillips, Eric S. Rawson, Neil P. Walsh, Ina Garthe, Hans Geyer, Romain Meeusen, Luc van Loon, Susan M. Shirreffs, Lawrence L. Spriet, Mark Stuart, Alan Vernec, Kevin Currell, Vidya M. Ali, Richard G.M. Budgett, Arne Ljungqvist, Margo Mountjoy, Yannis Pitsiladis, Torbjørn Soligard, Uğur Erdener and Lars Engebretsen

supplement dose is 20 g/day for 5 days, followed by 3 to 5 g/day to increase and maintain elevated body creatine levels ( Harris et al., 1992 ; Hultman et al., 1996 ). Enhanced adaptive response to exercise via increased growth factor/gene expression, increased intracellular water; reduced symptoms of or