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Hugo Ribeiro Zanetti, Lucas Gonçalves da Cruz, Camilo Luís Monteiro Lourenço, Giovana Castilho Ribeiro, Marco Aurélio Ferreira de Jesus Leite, Fernando Freitas Neves, Mário Leon Silva-Vergara and Edmar Lacerda Mendes


Highly active antiretroviral therapy (HAART) is associated with high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), triglyceride (TG), and C-reactive protein (CRP) levels. The natural course of the HIV infection reduces the high-density lipoprotein level (HDL-c). Thus, physical exercise plays a key role in reducing the effects of HAART and HIV.


Thirty people living with HIV (PLHIV) were randomized to the nonlinear resistance training (NLRT) and control (CON) groups. The NLRT group underwent 12 weeks of resistance training, whereas the CON group maintained usual daily activities. All volunteers underwent anthropometric, body composition, and biochemical assessments at the beginning and end of 12 weeks.


After 12 weeks, the NLRT group had increased lean body mass (P < .0001), and a reduction in body fat mass (P < .0001) and body fat percentage (P < .0001). The levels of TC (P < .0001), LDL-c (P = .049), TG (P < .0001), and CRP (P = .004) were reduced, and the HDL-c level increased (P < .0001).


Twelve weeks of NLRT causes beneficial changes in the body composition, lipid profile, and inflammation markers in PLHIV, and it can be used in this patient population.

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Rochelle R. Costa, Adriana C.K. Buttelli, Leandro Coconcelli, Laura F. Pereira, Alexandra F. Vieira, Alex de O. Fagundes, Juliano B. Farinha, Thais Reichert, Ricardo Stein and Luiz F.M. Kruel

Dyslipidemias are heterogeneous disorders of lipid metabolism arising from multiple etiologies that result in alterations in blood lipoproteins (low-density lipoprotein—LDL and high-density lipoprotein—HDL) and lipid (total cholesterol—TC and triglycerides—TG) concentrations. 1 In elderly women

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Susan Sullivan Glenney, Derrick Paul Brockemer, Andy C. Ng, Michael A. Smolewski, Vladimir M. Smolgovskiy and Adam S. Lepley

effects of exercise training on cardiovascular health. Traditional serum biomarkers, such as total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), glucose, C-reactive protein (CRP), insulin, and triglyceride levels, have been used to study the effects of exercise interventions

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Paul J. Collings, Diane Farrar, Joanna Gibson, Jane West, Sally E. Barber and John Wright

Glasgow Royal Infirmary, enzymatic reagents were used to determine serum concentrations of total cholesterol, triglycerides, HDL-c, low-density lipoprotein cholesterol (LDL-c), and very low-density lipoprotein cholesterol (Cobas C311 autoanalyzer; Roche Diagnostics, Basel, Switzerland). Cord blood

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Sang-Ho Lee, Steven D. Scott, Elizabeth J. Pekas, Jeong-Gi Lee and Song-Young Park

peripheral artery disease 12 ; serum low-density lipoprotein (LDL) and high-density lipoprotein (HDL) concentrations in healthy adults; 13 and LDL, HDL, total cholesterol, and TG levels in patients with type 2 hypercholesterolemia. 14 However, the potential beneficial effects of octacosanol intake for

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David C. Nieman, Courtney L. Capps, Christopher R. Capps, Zack L. Shue and Jennifer E. McBride

CK were measured in fresh serum samples using an AU5800 Clinical Chemistry System (Beckman Coulter, Brea, CA). Myoglobin was measured in fresh serum samples using an electrochemiluminescence immunoassay. Plasma-Oxidized Low-Density Lipoprotein and Ferric Reducing Ability of Plasma Oxidized low-density

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Jennifer Sygo, Alexandra M. Coates, Erik Sesbreno, Margo L. Mountjoy and Jamie F. Burr

. Secondary indicators of LEA were selected based on previous studies associating prolonged energy restriction, LEA, or menstrual disturbances with changes in glucose ( Melin et al., 2015 ), triiodothyronine ( Hulmi et al., 2017 ), low-density lipoprotein cholesterol ( Rickenlund et al., 2005 ), insulin

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Hyun-Tae Kim

We investigated the effect of long-term treatment (6 wk) with selenium and vitamin E, in combination with aerobic exercise training, on malondialdehyde (MDA), oxidized low-density lipoprotein (ox-LDL), and glutathione peroxi-dase (GPx) in STZ-induced diabetic rats. The rats were assigned randomly to one of three treatment groups (n = 12 per group): 1) exercise group (EX), 2) selenium/vitamin E/exercise group (SVE), and 3) selenium/vitamin E group (SV). To estimate the acute effect of exercise, a 30-min endurance exercise was used. The MDA concentration was significantly lower in the SVE. The ox-LDL was significantly lower in the SVE and SV. The hepatic concentrations of selenium and vitamin E were significantly higher in the SVE. These results indicate that the increase in MDA is mildly attenuated in rats that were aerobically trained. Moreover, the joint administration of selenium and vitamin E with or without exercise training reduces the levels of ox-LDL.

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Anatoli Petridou, Despina Lazaridou and Vassilis Mougios

Although chronic exercise is generally believed to improve the lipidemic profile, it is not clear whether this is due to exercise training or to other determinants such as the usually low body fat of athletes. The aim of the present study was to compare the lipidemic profile of young lean athletes and non-athletes matched for percentage body fat. Fourteen endurance athletes and fourteen sedentary men participated in the study. Participants provided two blood samples at the beginning and end of a 7-d period, during which they recorded physical activity and food intake. Athletes had significantly higher energy expenditure and energy intake but not significantly different macronutrient composition of their diet from non-athletes. No significant differences were found in serum triacylglycerol, total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol concentrations between groups. These data suggest that athletes and non-athletes with similar body fat do not differ in their lipidemic profiles.

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Rochelle D. Kirwan, Lindsay K. Kordick, Shane McFarland, Denver Lancaster, Kristine Clark and Mary P. Miles


The purpose of this study was to determine the dietary, anthropometric, blood-lipid, and performance patterns of university-level American football players attempting to increase body mass during 8 wk of training.


Three-day diet records, body composition (DEXA scan), blood lipids, and performance measures were collected in redshirt football players (N = 15, age 18.5 ± 0.6 yr) early season and after 8 wk of in-season training.


There was an increase (p < .05) from early-season to postseason testing for reported energy (+45%), carbohydrate (+82%), and protein (+29%) intakes and no change in the intake of fat. Fat intake was 41% of energy at the early-season test and 32% of energy at the postseason test. Increases (p < .05 for all) in performance measures, lean mass (70.5 ± 7.7–71.8 ± 7.7 kg), fat mass (15.9 ± 6.2–17.3 ± 6.8 kg), plasma total cholesterol (193.5 ± 32.4–222.6 ± 40.0 mg/dl), and low-density lipoproteins (LDL; 92.7 ± 32.7–124.5 ± 34.7 mg/dl) were measured. No changes were measured in triglycerides, very-low-density lipoproteins, or high-density lipoproteins.


Increases in strength, power, speed, total body mass, muscle mass, and fat mass were measured. Cholesterol and LDL levels increased during the study to levels associated with higher risk for cardiovascular disease. It is possible that this is a temporary phenomenon, but it is cause for concern and an indication that dietary education to promote weight gain in a manner less likely to adversely affect the lipid profile is warranted.