The loss of skeletal muscle mass in older adults is related to functional impairment, disability, and mortality ( Balogun et al., 2017 ; Baumgartner et al., 1998 ; Janssen, Heymsfield, & Ross, 2002 ). Evidence from sarcopenia-related research has increased, focusing on maintaining and improving
Chiharu Iwasaka, Tsubasa Mitsutake and Etsuo Horikawa
Trent J. Herda, Philip M. Gallagher, Jonathan D. Miller, Matthew P. Bubak and Mandy E. Parra
obese ( 34 ), and it is a worldwide health concern ( 37 ). Adipose infiltration in skeletal muscles of the lower extremity is linked to glucose metabolism and insulin sensitivity in adults ( 5 , 19 – 21 ). In the realm of insulin resistance in children, skeletal muscle is often overlooked despite the
Kyle L. Timmerman, Kevin D. Ballard, Michael A. Deal, Lisa C. Tagariello, Jenna M. Karrow, Gabrielle A. Volk, Adam Meisler, Ian D. Connors and Rachael E. Mott
older adults, 21 suggesting that PA may upregulate antioxidant defenses in older adults. To our knowledge, only one other study has examined the association between habitual PA and endogenous antioxidants in skeletal muscle. Nyberg et al 22 found greater skeletal muscle expression of SOD in older
Nicola Giovanelli, Lea Biasutti, Desy Salvadego, Hailu K. Alemayehu, Bruno Grassi and Stefano Lazzer
the skeletal muscle, as the exercise they analyzed was not isolated to a single muscle group (cycling at 1 and 1.5 W·kg −1 ). Thus, the purpose of the present study was to evaluate the effects of a trail-running race on muscle oxidative function by measuring pulmonary gas exchange variables and muscle
Stephan R. Fisher, Justin H. Rigby, Joni A. Mettler and Kevin W. McCurdy
. PubMed ID: 23626925 doi:10.1515/plm-2012-0032 10.1515/plm-2012-0032 23626925 2. Alves AN , Fernandes KPS , Deana AM , Bussadori SK , Mesquita-Ferrari RA . Effects of low-level laser therapy on skeletal muscle repair: a systematic review . Am J Phys Med Rehabil . 2014 ; 93 ( 12 ): 1073
Jeffrey J. Dueweke, Tariq M. Awan and Christopher L. Mendias
Eccentric-contraction-induced skeletal muscle injuries, included in what is clinically referred to as muscle strains, are among the most common injuries treated in the sports medicine setting. Although patients with mild injuries often fully recover to their preinjury levels, patients who suffer moderate or severe injuries can have a persistent weakness and loss of function that is refractory to rehabilitation exercises and currently available therapeutic interventions. The objectives of this review were to describe the fundamental biophysics of force transmission in muscle and the mechanism of muscle-strain injuries, as well as the cellular and molecular processes that underlie the repair and regeneration of injured muscle tissue. The review also summarizes how commonly used therapeutic modalities affect muscle regeneration and opportunities to further improve our treatment of skeletal muscle strain injuries.
Walter Herzog, Timothy Koh, Evelyne Hasler and Tim Leonard
We hypothesize that the neuromuscular system is designed to function effectively in accomplishing everyday movement tasks. Since everyday movement tasks may vary substantially in terms of speed and resistance, we speculate that agonistic muscles contribute differently to varying movement tasks such that the mechanical, structural, and physiological properties of the system are optimized at all times. We further hypothesize that a mechanical perturbation to the musculoskeletal system, such as the loss of an important joint ligament or the change of a muscle’s line of action, causes an adaptation of the system aimed at reestablishing effective function. Here. we demonstrate how the specificity of the cat ankle extensors is used to accommodate different locomotor tasks. We then illustrate how the loss of an important ligament in the cat knee leads to neuromuscular adaptation. Finally, we discuss the adaptability of skeletal muscle following an intervention that changes a muscle’s line of action, moment arm, and excursion.
Emily Arentson-Lantz, Elfego Galvan, Adam Wacher, Christopher S. Fry and Douglas Paddon-Jones
et al., 2011 ). To mimic the overt physical inactivity experienced during hospitalization, while separating the catabolic, disease-related effects from the intrinsic effects of skeletal muscle disuse, we subjected a cohort of healthy, community-dwelling older adults to a 7-day bed rest (BR) protocol
Alex S. Ribeiro, Ademar Avelar, Witalo Kassiano, João Pedro Nunes, Brad J. Schoenfeld, Andreo F. Aguiar, Michele C.C. Trindade, Analiza M. Silva, Luís B. Sardinha and Edilson S. Cyrino
synthesis and, thus, contribute to muscle mass accretion ( Farshidfar et al., 2017 ; Schoenfeld, 2010 ). The simultaneous analysis of changes in total body water (TBW) and its extracellular water (ECW) and ICW components may help explain the changes that occur in skeletal muscle mass (SMM) in response to
David T. Corr, Ray Vanderby Jr. and Thomas M. Best
An existing rheological model of skeletal muscle (Forcinito et al., 1998) was modified with a nonlinear Maxwell fluid element to provide a phenomenological model capable of analyzing the strain-stiffening behavior typically found in passive, and occasionally observed in active, skeletal muscle. This new model describes both active and passive muscular behavior as a combination of the behavior of each model component, without requiring prior knowledge of the force-length or force-velocity characteristics of the muscle.