Search Results

You are looking at 1 - 10 of 102 items for :

  • "total cholesterol" x
Clear All
Restricted access

Yandiswa Y. Yako, Mogamat S. Hassan, Rajiv T. Erasmus, Lize van der Merwe, Susan Janse van Rensburg and Tandi Edith Matsha

Background:

There is evidence demonstrating that the contribution of sedentary behavior and effect of physical activity on metabolic phenotypes is mediated by polymorphisms in genes.

Methods:

The type and frequency of physical activity was assessed by means of structured questionnaires in 1555 South African school learners. Anthropometric measurements, blood pressure, fasting blood glucose and lipids were measured using standard procedures. The effect of different types and frequency of physical activity on obesity-related traits was assessed in relation to MC3R T6K and V81I genotypes in 430 of the learners.

Results:

Levels of total cholesterol were significantly lower in learners carrying the MC3R T6K and V81I minor alleles, after adjusting for age, race, gender, and each specific physical activity category. An activity-by-genotype interaction was also detected: learners heterozygous for the V81I polymorphism and performed house chores often had reduced total cholesterol. Though no association was observed between frequency of physical activity and BMI, television viewing was significantly associated with an increase in height, weight and marginally with waist circumference.

Conclusion:

Our findings suggest that physical activity even in the form of house chores has a positive effect on metabolic traits and this effect is further enhanced in the presence of MC3R polymorphisms.

Restricted access

Hugo Ribeiro Zanetti, Lucas Gonçalves da Cruz, Camilo Luís Monteiro Lourenço, Giovana Castilho Ribeiro, Marco Aurélio Ferreira de Jesus Leite, Fernando Freitas Neves, Mário Leon Silva-Vergara and Edmar Lacerda Mendes

Background:

Highly active antiretroviral therapy (HAART) is associated with high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), triglyceride (TG), and C-reactive protein (CRP) levels. The natural course of the HIV infection reduces the high-density lipoprotein level (HDL-c). Thus, physical exercise plays a key role in reducing the effects of HAART and HIV.

Methods:

Thirty people living with HIV (PLHIV) were randomized to the nonlinear resistance training (NLRT) and control (CON) groups. The NLRT group underwent 12 weeks of resistance training, whereas the CON group maintained usual daily activities. All volunteers underwent anthropometric, body composition, and biochemical assessments at the beginning and end of 12 weeks.

Results:

After 12 weeks, the NLRT group had increased lean body mass (P < .0001), and a reduction in body fat mass (P < .0001) and body fat percentage (P < .0001). The levels of TC (P < .0001), LDL-c (P = .049), TG (P < .0001), and CRP (P = .004) were reduced, and the HDL-c level increased (P < .0001).

Conclusion

Twelve weeks of NLRT causes beneficial changes in the body composition, lipid profile, and inflammation markers in PLHIV, and it can be used in this patient population.

Restricted access

Susan Sullivan Glenney, Derrick Paul Brockemer, Andy C. Ng, Michael A. Smolewski, Vladimir M. Smolgovskiy and Adam S. Lepley

effects of exercise training on cardiovascular health. Traditional serum biomarkers, such as total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), glucose, C-reactive protein (CRP), insulin, and triglyceride levels, have been used to study the effects of exercise interventions

Restricted access

Inès Boukabous, Alexis Marcotte-Chénard, Taha Amamou, Pierre Boulay, Martin Brochu, Daniel Tessier, Isabelle Dionne and Eléonor Riesco

containing ethylenediaminetetraacetic acid or a coagulation activator gel (depending on the variables measured). Fasting lipid profile (triglycerides, total cholesterol, high-density lipoprotein cholesterol [HDL-C], non-HDL-C, and low-density lipoprotein cholesterol [LDL-C]) as well as glucose and insulin

Restricted access

Rochelle R. Costa, Adriana C.K. Buttelli, Leandro Coconcelli, Laura F. Pereira, Alexandra F. Vieira, Alex de O. Fagundes, Juliano B. Farinha, Thais Reichert, Ricardo Stein and Luiz F.M. Kruel

Dyslipidemias are heterogeneous disorders of lipid metabolism arising from multiple etiologies that result in alterations in blood lipoproteins (low-density lipoprotein—LDL and high-density lipoprotein—HDL) and lipid (total cholesterol—TC and triglycerides—TG) concentrations. 1 In elderly women

Restricted access

Evelin Lätt, Jarek Mäestu and Jaak Jürimäe

Blood Samples Venous blood samples were taken after an overnight fast and stored at −80°C before analysis. Total cholesterol (in millimoles per liter), high-density lipoprotein (mmol/L), low-density lipoprotein (in millimoles per liter), and triglycerides (TRG; in millimoles per liter) were analyzed by

Restricted access

Rochelle Rocha Costa, Adriana Cristine Koch Buttelli, Alexandra Ferreira Vieira, Leandro Coconcelli, Rafael de Lima Magalhães, Rodrigo Sudatti Delevatti and Luiz Fernando Martins Kruel

the effects of isolated ST on lipid (total cholesterol [TC], HDL, low-density lipoprotein [LDL], and TG) and inflammatory marker profiles (CRP and adiponectin) in adults with the use of a control group. Methods This systematic review was conducted using a predetermined protocol established according

Restricted access

Clarice Martins, Francisco Silva, Maria Paula Santos, José Carlos Ribeiro and Jorge Mota

This study analyzes trends in CVD risk factors and aerobic performance. Two cross-sectional studies were performed including 138 (58 boys and 80 girls) in 1998 and 110 (44 boys and 66 girls) in 2003 adolescents. Although in cardiorespiratory fitness (CRF) boys performed better than girls, they had lower body mass index (BMI) and total cholesterol (TC) than girls. The data also showed a significant year effect (p = .000) for CRF in both boys and girls. The sex–age group interaction was not significant (p > .05). This cross-sectional study revealed a marked low CRF level over time in both boys and girls.

Restricted access

Soyang Kwon, Trudy L. Burns and Kathleen Janz

Background:

This study aimed to examine combined and independent effects of cardiorespiratory fitness and fatness on cardiovascular risk factors among U.S. adolescents.

Methods:

Data from adolescents age 12 to 19 years participating in the NHANES 1999 to 2002 were used. Fitness level was determined by submaximal treadmill test and was dichotomized as ‘not fit’ or ‘fit’ according to the FITNESSGRAM. Fatness level was categorized as ‘not fat’ or ‘fat’ based on the CDC BMI growth charts. Gender-specific multivariable linear regression analyses were conducted to compare age-, race/ethnicity-, fatness-, and waist circumference-adjusted means of blood pressure, lipids, lipoproteins, C-peptide, insulin, and C-reactive protein (CRP) levels.

Results:

A total of 3202 adolescents (1629 boys) were included for data analysis. Among boys, total cholesterol, tri-glycerides, insulin, and CRP mean levels were significantly higher (P < .05) in the ‘not fit’ group than in the ‘fit’ group, after adjustment for fatness level and waist circumference. Among girls, the fatness level- and waist circumference-adjusted means of total cholesterol (P < .01) and LDL-C (P < .09) were higher in the ‘not fit’ than ‘fit’ groups.

Conclusion:

Cardiorespiratory fitness, independent of fatness, may have beneficial effects on lipid profiles among girls, and on lipid profiles, insulin metabolism, and inflammation levels among boys.

Restricted access

Roger G. Bounds, Steven E. Martin, Peter W. Grandjean, Barbara C. O’Brien, Cindi Inman and Stephen F. Crouse

To test the effect of diet on the short-term lipid response to exercise, fourteen moderately trained (VO2max: 50.2 ± 6.7 ml/kg/min), healthy men (mean age: 28 ± 4 years) were alternately fed a high fat (60±6.7% fat) and a high carbohydrate (63 ± 3.2% carbohydrate) isoenergetic diet for 2 weeks in a randomized crossover design. During the last 4 days of the treatments, fasting total cholesterol, triglyceride. HDL-cholesterol, and HDL3-cholesterol were measured the day before, and again immediately, 24 hr. and 48 hr after exercise (4190 kJ, 70% VO2max). LDL-cholesterol and HDL2-cholesterol were calculated. Lipid concentrations were adjusted for plasma volume changes after exercise. A 2 (diet) × 4 (time) ANOVA with repeated measures revealed no significant interaction between the diet and exercise treatments. Furthermore, diet alone did not influence lipid concentrations in these trained men. Exercise resulted in an increase in HDL-C (10.7%) and HDL3-C (8.5%) concentrations and a concomitant fall in triglyceride (-25%) and total cholesterol (-3.5%). Thus, we conclude that diet composition does not affect the short-term changes in blood lipids and lipoproteins that accompany a single session of aerobic exercise in moderately trained men.